|
Post by Andrew on Aug 6, 2015 17:32:02 GMT 10
Hi Tom,
I was hoping to ask you a specific question in relation to the WBC and Neutrophils and Lymphocytes ratios on a Blood Profile.
When considering the following (taken from your Interpretation page), do you also consider the readings of the WBC also?
In other words a situation can exist where for instance the Lymphocytes count is 0.8 and the Neutrophils is 4.5, and at 4.5 is within the preferred range, however with a Lymphocytes count of 0.8 the Neutrophils count should not be much higher than 3.0, and therefore a low grade bacterial infection should be suspected. The same applies if the situation was reversed between Neutrophils and Lymphocytes counts, and a low grade viral infection should be suspected.
Say we have a profile that shows the below readings.
White Cell Count 5.9
Neutrophils 3.2 Lymphocytes 2.5 Monocytes 0.2
From reading the Interpretation page, the WBC count is slightly elevated (3.5-5.5) which could be caused by a slight bacterial infection, but the split between the Neutrophils and Lymphocytes is suggesting a possible low grade viral infection.
This has come up a couple of times lately and has left me slightly confused. Looking forward to hearing your thoughts.
|
|
|
Post by Tom Meulman on Aug 8, 2015 7:04:18 GMT 10
Hi Andrew,
Total white cell count slightly elevated. Neutrophils 3.2 which is within acceptable limits. Lymphocytes 2.5 which is too high and indicates a viral infection, keeping in mind that quite often a viral infection can result in a bacterial secondary infection.
Regardless of the balance between neutrophils and lymphocytes the individual levels are what really counts, the balance example I used was simply to demonstrate that various levels of substances within a blood profile should not be simply looked at individually, but should be looked at in conjunction with all other information gained.
Cheers, Tom
|
|
|
Post by HAKKIM on Aug 10, 2016 2:33:17 GMT 10
Dear Tom, I am new for biomedical and I have some doubts. Please ensure relation between the following blood parameters and how to calculate lym%,MXD% Using WBC
1) Whole WBC (white blood cell) 2) 2) LYM% [W-SCR] (WBC-Small Cell Ratio) Ratio (%) of lymphocytes (small cells) to whole WBC 3) MXD% [W-MCR] (WBC-Middle Cell Ratio) Ratio (%) of the summation of basophils, eosinophils and monocytes (middle cells) to whole WBC 4) NEUT% [W-LCR] (WBC-Large Cell Ratio) Ratio (%) of neutrophils (large cells) to whole WBC 5) LYM# [W-SCC] (WBC-Small Cell Count) Absolute count of lymphocytes (small cells) in 1 L of whole blood 6) MXD# [W-MCC] (WBC-Middle Cell Count) Absolute count of the basophils, eosinophils and monocytes (middle cells) in 1 L of whole blood 7) NEUT# [W-LCC] (WBC-Large Cell Count) Absolute count of neutrophils (large cells) in 1 L of whole blood 8) RBC (red blood cell) (Analysis principle: DC detection method) RBC count in 1 L of whole blood 9) HGB (Hemoglobin) (Analysis principle: Non-Cyanide hemoglobin analysis method) Volume (gram) of hemoglobin in 1 dL of whole blood 10) HCT (Hematocrit value) (Analysis principle: RBC pulse height detection method) Ratio (%) of whole RBC volume in whole blood 11) MCV (Mean RBC volume) Mean RBC volume (fL) in whole blood, which is calculated by Hct/RBC. 12) MCH (Mean RBC hemoglobin) Mean hemoglobin volume (pg) per RBC, which is calculated by Hgb/RBC. 13) MCHC (Mean RBC hemoglobin concentration) Mean hemoglobin concentration (g/dL), which is calculated by Hgb/Hct. 14) RDW-CV (RBC distribution width - CV) RBC distribution width (%) calculated from the points defining 68.26% of the entire area spreading from the peak of the RBC particle distribution curve. 15) RDW-SD (RBC distribution width - SD) The distribution width (fL) at the height of 20% from the bottom when the peak RBC particle distribution curve is taken as 100%. 16) PLT (Platelet) (Analysis principle: DC detection method) Platelet count in 1 L of whole blood 17) PDW (Platelet distribution width)* The distribution width (fL) at the height of 20% from the bottom with the peak of platelet particle distribution curve taken as 100%. 18) MPV (Mean platelet volume) Mean volume of platelet (fL) 19) P-LCR (Large platelet ratio) * Ratio (%) of large platelet volume exceeding 12 fL to the platelet volume
|
|
|
Post by Tom Meulman on Aug 15, 2016 4:34:29 GMT 10
Hi HAKKIM,
Sorry mate but answering that type of question is way beyond the scope of and intent of this website and just not possible to answer.
Cheers, Tom
|
|