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Post by Tom Meulman on Jun 5, 2015 6:46:41 GMT 10
The Racing Analytical Services website provides a list of the supplementary compounds tested for in a swab. Racing Analytical Services Cheers, Tom
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Post by Jeffro on Jul 25, 2015 11:16:54 GMT 10
Hi Tom, I would assume that this list is not specific for greyhounds as I would assume that Ibuprofen, Caffeine and Dimethyl sulfoxide (DMSO) would be on that list. Would this list be for sports people that they are testing for??
So the greyhounds would be tested for all the substances on that list plus extras???
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Post by Tom Meulman on Jul 25, 2015 16:13:56 GMT 10
Hi Jeffro,
You are right there are a few substances such as caffeine that are swabbed for in greyhounds but not routinely in human athletes. I must admit I did not go through the list to check on that. Thanks for posting that information.
Cheers, Tom
PS: all we can say for sure is that the substances on the list are capable of being detected in a swab, what is actually tested for when they test a swab from a racing greyhound is not publicly disclosed, and therefore anyone's guess.
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Post by Jeffro on Sept 2, 2015 15:26:14 GMT 10
Hi Tom, Would there be any idea on how the new cobalt threshold level will effect some trainers how have been preparing greyhounds in the past. I have seen people stating to go over the level set you would need to give the dogs an excessive amount of product, but after looking at the dogs site in NSW it seems that this might not be the case. VAM is the product that seems to have a massive effect on levels and looks like they are recommending a minimum withholding time of 96 hours prior to racing.
Would be very keen to hear your thoughts of this new level they are going to bring in
Here is a few of the test results that they have published:
The following administration studies were performed on six greyhounds:
VAM® Paste VAM® Paste (CEVA) is a commercially available product registered as a supplement (vitamins, amino acids and minerals) paste. The cobalt salt is cobalt sulfate (240 µg/mL) and contains cyanocobalamin (150 µg/mL). This is equivalent to around 98 µg/mL of cobalt. The manufacturer’s recommended dose rate in dogs is 0.25-1mL per 10kg bodyweight, twice weekly, administered orally.
Dose administered: 1mL/10kg, administered orally on two occasions on alternate days. This is equivalent to a dose rate of 24 µg/kg of cobalt sulfate.
Results: Cobalt levels detected above the 100 ng/mL threshold (maximum 317 ng/mL) for up to 6 hours after the second dose, but did not return to resting levels for 24 hours. A cumulative effect may occur with this product. A minimum withholding period of 24 hours is suggested.
VAM® Injection VAM® Injection (CEVA) is a commercially available product registered as a supplement (vitamins, amino acids and minerals) injection. The cobalt salt is cobalt sulfate (240 µg/mL) and contains cyanocobalamin (150 µg/mL). This is equivalent to around 98 µg/mL of cobalt. The manufacturer’s recommended dose rate in dogs is 0.25-1mL per 10kg bodyweight, twice weekly, administered intramuscularly.
Dose administered: 1mL/10kg, administered intramuscularly on two occasions on alternate days. This is equivalent to a dose rate of 24 µg/kg of cobalt sulfate
Results: Cobalt levels detected above the 100 ng/mL threshold (maximum 6523 ng/mL) for up to 48 hours after the second dose, but did not return to resting levels for at least 72 hours. A cumulative effect may occur with this product. A minimum withholding period of 96 hours is suggested.
Hemo-15® Injection Hemo-15® (Virbac) is a commercially available product registered as a supplement (iron, amino acid and B-vitamin) injection. The cobalt salt is cobalt gluconate (0.7 mg/mL) and contains cyanocobalamin (150 µg/mL). This is equivalent to around 99 µg/mL of cobalt. The manufacturer’s recommended dose rate (in horses) is 1mL per 50kg of bodyweight, administered intravenously.
Dose administered: 1mL, administered intravenously, once per day for three days. This is equivalent to a dose rate of 20 µg/kg of cobalt gluconate, based on a 35kg dog.
Results: Cobalt levels detected above the 100 ng/mL threshold (maximum 1350 ng/mL) for up to 24 hours after the third dose, but did not return to resting levels for 48 hours. A cumulative effect may occur with this product. A minimum withholding period of 48 hours is suggested.
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Post by Tom Meulman on Sept 4, 2015 19:49:08 GMT 10
Thanks Jeffro great information and pretty well self explanatory and detailed in regard to detectable levels. However all I can say is that it is certainly becoming more and more difficult to train greyhounds to produce their very best on the race track and not fall foul of regulations in regard to prohibited substances. A few years ago no one would have believed that high cobalt levels would become a positive swab. This is an interesting read for those that can handle a bit of heavy going. bjsm.bmj.com/content/39/11/872.fullCheers, Tom
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Post by Guest on Sept 27, 2015 18:22:33 GMT 10
Hi Tom,
If I mix DMSO with Zeng Gu Shui and brush that mix on to a greyhounds wrist lightly what would be the witholding period on the DMSO so I avoid a positive swab?
I am also keen to know what the witholding period of Rimadyl 50mg tablets are?
Thanks
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Post by Tom Meulman on Sept 28, 2015 11:23:33 GMT 10
Hi Guest,
Mixing a product that is designed to create warmth on the skin surface with DMSO is scary, as anything mixed with DMSO is pulled through the skin and then has to enter blood vessels to be eliminated from the body via the kidneys. This may cause kidney damage and be toxic to the liver.
In regard to withholding times for any drug I'm sorry but I'm not able to provide any guidelines as this has to come from official sources.
Cheer, Tom
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